Cell Replication (HSC SSCE Biology): Flashcards

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DNA Replication: The Watson and Crick Model
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DNA replication result

Two identical copies of DNA from one original molecule

When DNA replication occurs

During interphase, before cell division

Semi-conservative replication meaning

Each new DNA has one original strand and one new strand

Helicase function in DNA replication

Unwinds the double helix and breaks hydrogen bonds between bases

DNA polymerase III function

Builds new DNA strands by adding nucleotides to the 33' end

Ligase function in DNA replication

Joins Okazaki fragments together on the lagging strand

Leading strand synthesis pattern

Synthesised continuously in one long chain

Lagging strand synthesis pattern

Synthesised discontinuously in short fragments (Okazaki)

Okazaki fragments

Short DNA segments (100100-150150 nucleotides) on lagging strand

DNA base pairing rules

Adenine pairs with thymine; guanine pairs with cytosine

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