Defences Against Infection in Animals (OCR A-Level Biology A): Flashcards

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Defences Against Infection in Animals
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Three lines of defence

1st: barriers, 2nd: non-specific, 3rd: specific (lymphocytes)

First line of defence

Physical/chemical barriers preventing pathogen entry

Lysozyme function

Enzyme that breaks down bacterial cell walls

Neutrophils

Short-lived phagocytes, rapid reaction force, 60-70% of WBCs

Cause of inflammation

Mast cells secrete histamine causing vasodilation & swelling

B lymphocyte maturation site

Bone marrow

Plasma cell

Activated B cell that produces and releases antibodies

Clonal expansion

Mitotic division of lymphocytes forming larger clones

IgG antibody structure

4 polypeptides: 2 heavy (long) and 2 light (short) chains

Active vs passive immunity

Active: body makes Ab (long-term); Passive: receives Ab (temp)

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