Effects of Drugs on Synapses (AQA A-Level Biology): Flashcards
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How many main ways can drugs modify synaptic transmission?
How many main ways can drugs modify synaptic transmission?
Five main ways
How do agonist drugs work?
How do agonist drugs work?
Mimic neurotransmitters, bind receptors, trigger response
Example of agonist drug
Example of agonist drug
Nicotine (mimics acetylcholine)
How do antagonist drugs work?
How do antagonist drugs work?
Block receptors, prevent neurotransmitter activation
Curare effect
Curare effect
Muscle paralysis (blocks acetylcholine receptors)
Enzyme inhibition effect at synapse
Enzyme inhibition effect at synapse
Prevents neurotransmitter breakdown, prolongs action
Example of enzyme inhibitor
Example of enzyme inhibitor
Nerve gases (stop acetylcholinesterase)
Drug stimulating neurotransmitter release
Drug stimulating neurotransmitter release
Amphetamines
Drug inhibiting neurotransmitter release
Drug inhibiting neurotransmitter release
Alcohol
Enzyme breaking down acetylcholine
Enzyme breaking down acetylcholine
Acetylcholinesterase