Manufacture of Aspirin (AQA A-Level Chemistry): Flashcards

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Manufacture of Aspirin
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Type of reaction to synthesise aspirin

Acylation reaction

Two reactants for aspirin synthesis

Salicylic acid and ethanoic anhydride

Group salicylic acid provides for acylation

Phenolic group

Role of ethanoic anhydride in aspirin synthesis

Acylating agent

Two products of aspirin synthesis

Aspirin and ethanoic acid

Type of compound aspirin is

Ester

Nature of ethanoic acid by-product

Mild and non-corrosive

Cost of ethanoic anhydride vs ethanoyl chloride

Cheaper to produce

Reactivity: ethanoic anhydride vs ethanoyl chloride

Less reactive

By-product from ethanoyl chloride reaction

Hydrogen chloride gas (highly corrosive and hazardous)

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