Amino acids, Proteins & DNA (A Level only) (AQA A-Level Chemistry): Flashcards

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Enzymes
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What are enzymes?

Proteins that catalyse biochemical reactions

What structure do most enzymes have?

Globular

What is an active site?

Small crevice/pocket where substrate binds

What is enzyme stereospecificity?

Catalyses only one enantiomer of chiral substrate

What is an enzyme-substrate complex?

Forms when substrate binds to enzyme's active site

How do enzymes speed up reactions?

Lower activation energy via alternative pathway

What is activation energy?

Minimum energy needed for successful reaction

What are enzyme inhibitors?

Molecules blocking active site, preventing substrate binding

How do enzyme-inhibiting drugs work?

Mimic substrate, bind to active site, block real substrate

What tool is used to design enzyme inhibitors?

Computer modelling of 3D enzyme structure

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