Enzymes (OCR A-Level Biology A): Flashcards
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Cofactor definition
Cofactor definition
Non-protein substance required by enzyme for catalytic function
Coenzyme definition
Coenzyme definition
Small organic non-protein molecule acting as cofactor
Prosthetic group definition
Prosthetic group definition
Cofactor permanently attached to enzyme molecule
Prosthetic group in carbonic anhydrase
Prosthetic group in carbonic anhydrase
Zinc ion (Zn²⁺)
Competitive inhibitor definition
Competitive inhibitor definition
Molecule with similar structure competing for active site
How to overcome competitive inhibition
How to overcome competitive inhibition
Increase substrate concentration
Non-competitive inhibitor binding site
Non-competitive inhibitor binding site
Allosteric site (not active site)
Can substrate overcome non-competitive inhibition?
Can substrate overcome non-competitive inhibition?
No
Enzyme inhibited by cyanide
Enzyme inhibited by cyanide
Cytochrome oxidase
Enzyme inhibited by statins
Enzyme inhibited by statins
HMG-CoA reductase