Preparation of Amines (AQA A-Level Chemistry): Flashcards

Ammonia ($NH₃$) with H replaced by alkyl/aryl groups

One H of $NH₃$ replaced by alkyl/aryl group

Two H atoms of $NH₃$ replaced by alkyl/aryl groups

Three H atoms of $NH₃$ replaced by alkyl/aryl groups

Makes amines act as nucleophiles and bases

Nucleophilic substitution with $NH₃$ or nitrile reduction

Excess $NH₃$ in ethanol, heated under pressure

$LiAlH₄$ in dry ether or $H₂$ with Pd/Pt/Ni catalyst

50-55°C with conc. $HNO₃$ and $H₂SO₄$

Sn + conc. HCl under reflux, then NaOH