Nucleophilic Substitution (AQA A-Level Chemistry): Flashcards

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Nucleophilic Substitution
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Definition of nucleophile

Species donating lone pair to form covalent bond

Conditions for halogenoalkane + OH−OH^{-} reaction

Aqueous and warm

Product of halogenoalkane + CN−CN^{-}

Nitrile (lengthens carbon chain)

Conditions for halogenoalkane + NH3NH_3

Excess NH3NH_3 in ethanol, heat in sealed flask

Why sealed flask for NH3NH_3 + halogenoalkane?

Ammonia would escape as a gas

Effect of excess NH3NH_3 in amine formation

Primary amine is major product

Use of quaternary ammonium salts

Cationic surfactants

Cationic surfactant structure

Charged head (hydrophilic) + hydrocarbon tail (hydrophobic)

NN property in quaternary ammonium salt

Positively charged, no lone pair

Product of amine + acyl chloride

Amide

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