Cell Signalling (OCR A-Level Biology A): Flashcards
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Cell signalling definition
Cell signalling definition
Communication between cells via chemical messengers
Primary receptor type for cell signalling
Primary receptor type for cell signalling
Glycoproteins
How many messenger types can one receptor bind?
How many messenger types can one receptor bind?
Only one type (receptor specificity)
Target cell definition
Target cell definition
Cell with appropriate receptors that responds to a messenger
3 mechanisms of receptor action
3 mechanisms of receptor action
Second messengers, ion channels, enzyme activation
% of medicinal drugs targeting membrane receptors
% of medicinal drugs targeting membrane receptors
Approximately 50%
How antihistamines work
How antihistamines work
Competitive inhibition of histamine receptors
Natural compounds that bind opioid receptors
Natural compounds that bind opioid receptors
Enkephalins
Why morphine binds to membrane surface
Why morphine binds to membrane surface
Water-soluble, cannot cross lipid bilayer
How naloxone reverses morphine effects
How naloxone reverses morphine effects
Competitive inhibition of opioid receptors