DNA Sequencing and Profiling (OCR A-Level Biology A): Quizzes
📚Quizzes
Practise the questions
10 questions from this quiz
ShowHide
Practise the questions
10 questions from this quiz
What do dideoxynucleotides lack that causes DNA synthesis termination in chain-termination sequencing?
What do dideoxynucleotides lack that causes DNA synthesis termination in chain-termination sequencing?
3' hydroxyl group
How many capillary flow electrophoresis apparatus run in parallel in high-throughput sequencing machines?
How many capillary flow electrophoresis apparatus run in parallel in high-throughput sequencing machines?
96
What percentage of chain termination cost does next-generation sequencing reduce to for 1.0 megabase pairs?
What percentage of chain termination cost does next-generation sequencing reduce to for 1.0 megabase pairs?
0.1%
Which organism was first successfully sequenced using the shotgun sequencing approach?
Which organism was first successfully sequenced using the shotgun sequencing approach?
Haemophilus influenzae
How does nanopore sequencing identify different DNA bases?
How does nanopore sequencing identify different DNA bases?
Each base alters electrical current flow
How many nucleotides long are STRs and how many times are they typically repeated?
How many nucleotides long are STRs and how many times are they typically repeated?
2-5 nucleotides repeated 10-30 times
What does the European DNA 17 profile consist of for forensic identification?
What does the European DNA 17 profile consist of for forensic identification?
16 STR loci plus sex markers
Why do most people show two peaks for most STR loci in their profile?
Why do most people show two peaks for most STR loci in their profile?
They're heterozygous with different alleles
Approximately what percentage of genetic variation in humans do SNPs comprise?
Approximately what percentage of genetic variation in humans do SNPs comprise?
90%
Approximately how frequently do SNPs occur in the human genome?
Approximately how frequently do SNPs occur in the human genome?
Every 100-300 base pairs