Enzyme Inhibition (AQA A-Level Biology): Flashcards

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Enzyme Inhibition
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Effect of enzyme inhibitors

Reduce enzyme activity

Two types of enzyme inhibition

Competitive and non-competitive

Competitive inhibitor shape

Similar to substrate

Competitive inhibitor binding site

Active site

Effect of high substrate concentration on competitive inhibition

Overcomes/reduces inhibition

Non-competitive inhibitor binding site

Allosteric site

How do non-competitive inhibitors affect enzymes?

Change enzyme shape

Effect of increasing substrate concentration on non-competitive inhibition

Cannot overcome it

End-product inhibition

Final product inhibits first enzyme in pathway

End-product inhibition type

Non-competitive

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