Carboxylic Acid Derivatives (OCR A-Level Chemistry A): Flashcards

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Carboxylic Acid Derivatives
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Define carboxylic acid derivative

Compound that can be hydrolysed to form parent carboxylic acid

Structure of acyl group

R-C=O\text{R-C=O}

Four types of carboxylic acid derivatives

Esters, acyl chlorides, acid anhydrides, amides

Ester naming rule order

Alcohol part first, then acid part

Esterification reaction conditions

Heat under reflux, conc. H2SO4\text{H}_2\text{SO}_4 catalyst

Alkaline hydrolysis of ester produces?

Carboxylate salt + alcohol (irreversible)

Reagent to prepare acyl chlorides from carboxylic acids

Thionyl chloride (SOCl2\text{SOCl}_2)

Why are acyl chlorides highly reactive?

Cl is good leaving group, C=O carbon is δ+\delta^+

Moles of NH3\text{NH}_3 needed per mole acyl chloride

2 moles (one forms amide, one neutralises HCl)

Shape changes in nucleophilic addition-elimination

Trigonal planar → tetrahedral → trigonal planar

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