Acylation (AQA A-Level Chemistry): Quizzes

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Acylation
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What functional group does an acyl group (RCOR-CO-) consist of?

Carbonyl (C=OC=O) attached to alkyl/aryl

What is the general formula for acyl chlorides?

RCOClR-COCl

Which acyl compound is the most reactive towards nucleophiles?

Acyl chlorides

What are the products when ethanoyl chloride reacts with water?

Ethanoic acid and HClHCl

Why are acid anhydrides preferred over acyl chlorides in industrial synthetic routes?

Acyl chlorides easily hydrolysed by water

In the carbonyl group of acyl compounds, what is the charge on the carbon atom?

Partially positive (δ+δ+)

What are the products when ethanoyl chloride reacts with ethanol?

Ester and HClHCl

How many ammonia molecules react with one acyl chloride molecule in the overall reaction?

2

What is an N-substituted amide?

Hydrocarbon group substituted H on NH2NH_2

Why is ethanoic anhydride preferred over ethanoyl chloride for making aspirin?

Cheaper, less corrosive, easier to control

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