Thyroxin (negative feedback) (Edexcel GCSE Biology): Flashcards

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Thyroxin (negative feedback)
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Gland that produces thyroxine

Thyroid gland

Main role of thyroxine hormone

Controls metabolic rate

Definition of metabolic rate

Speed at which chemical reactions occur in body

Other role of thyroxine besides metabolic rate

Supports growth and development

Process that regulates thyroxine levels

Negative feedback

Brain structure that detects thyroxine levels

Hypothalamus

Hormone released by hypothalamus (abbreviation)

TRH (thyrotropin-releasing hormone)

Hormone released by pituitary gland (abbreviation)

TSH (thyroid-stimulating hormone)

Location of thyroid gland in body

Neck

Effect of high thyroxine on TRH & TSH production

Inhibits/stops production

Sequence: low thyroxine triggers release of

TRH, then TSH, then more thyroxine

Why underactive thyroid causes weight gain

Less thyroxine → lower metabolic rate → fat storage

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