Monoclonal antibodies (Edexcel GCSE Biology): Flashcards
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What are monoclonal antibodies?
What are monoclonal antibodies?
Identical antibodies from same immune cell
How many protein antigens do monoclonal antibodies bind to?
How many protein antigens do monoclonal antibodies bind to?
Only one specific protein antigen
Example medical use of monoclonal antibodies
Example medical use of monoclonal antibodies
Pregnancy testing
Lymphocyte properties in antibody production
Lymphocyte properties in antibody production
Make antibodies but cannot divide
Tumour cell properties in production
Tumour cell properties in production
Divide rapidly but don't make antibodies
Cell formed: lymphocytes + tumour cells
Cell formed: lymphocytes + tumour cells
Hybridoma
What type of cell produces antibodies?
What type of cell produces antibodies?
B-lymphocytes
Why hybridoma antibodies are identical
Why hybridoma antibodies are identical
Produced from clones of same cell
Structure of proteins in blood clots
Structure of proteins in blood clots
Solid mesh
What is attached to antibodies to detect blood clots?
What is attached to antibodies to detect blood clots?
Radioactive element
Lab use: monoclonal antibodies measure
Lab use: monoclonal antibodies measure
Hormone/chemical levels in blood
What is bound to antibodies for lab detection?
What is bound to antibodies for lab detection?
Fluorescent dye
Blood screening example using monoclonal antibodies
Blood screening example using monoclonal antibodies
HIV infections
Research use of monoclonal antibodies
Research use of monoclonal antibodies
Find/identify molecules on cells or tissue
Research detection method used
Research detection method used
Look for fluorescence buildup